TimesFM: Google Research Pretrained Time-Series Foundation Model
TimesFM is a pretrained foundation model developed by Google Research specifically for time-series forecasting tasks. The repository has accumulated over 20,000 GitHub stars with 99 new stars today, indicating sustained community interest. It represents Google Research's effort to apply the foundation model paradigm to time-series data rather than language or vision.
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Toto 2.0: Open-Weights Time Series Foundation Models Demonstrate Scaling Laws from 4M to 2.5B Parameters
Datadog releases Toto 2.0, a family of five open-weights time series forecasting models ranging from 4M to 2.5B parameters, demonstrating consistent forecast quality improvements with scale. The models achieve state-of-the-art results on three benchmarks: BOOM (observability), GIFT-Eval (general-purpose), and TIME (contamination-resistant). The release includes architectural details, a u-muP hyperparameter transfer pipeline, and all base checkpoints under Apache 2.0 license.
Foundation Model for Wearable Health Data Pretrained on 1 Trillion Minutes from 5 Million Participants
Researchers propose a large-scale foundation model for wearable health data, pretrained on over one trillion minutes of unlabeled sensor signals from five million participants. The model demonstrates systematic performance improvements across 35 health prediction tasks spanning cardiovascular, metabolic, sleep, and mental health domains, with joint scaling of model capacity and data volume. A 'classroom' of LLM agents autonomously searches downstream predictive head configurations, and the resulting embeddings are integrated into a Personal Health Agent validated by 1,860 clinician ratings. The work establishes label-efficient few-shot learning and generative capabilities for daily health metric estimation.
Probabilistic Time Series Forecasting with Transformers
This Hugging Face blog post introduces probabilistic time series forecasting using Transformer-based models available in the Hugging Face ecosystem. It covers the application of attention-based architectures to sequential prediction tasks with uncertainty quantification. The post serves as a tutorial and capability demonstration for time series modeling within the Transformers library.
TxFM: Masked Autoencoding Foundation Model for RNA-seq Gene Expression Representation
The paper introduces TxFM, a self-supervised masked autoencoder model for transcriptomic (RNA-seq) data representation learning, trained on a curated 1.4M-sample corpus called DiverseRNA-1.4M. TxFM outperforms existing transcriptomic foundation models trained on datasets over 100x larger, addressing the known problem of deep models underperforming linear baselines on gene expression data. The work provides ablation studies identifying critical architecture choices and argues that careful data curation combined with inductive self-supervised learning is sufficient for strong transfer performance in transcriptomics.
Benchmark of deep learning architectures for multi-horizon behavioural forecasting in mobile health
A new arXiv preprint benchmarks six deep learning architectures, two zero-shot foundation models, and statistical baselines on multi-horizon behavioural forecasting from wearable and smartphone data across 800+ participants. Key findings include: no single architecture dominates (PatchTST leads among trained models), TimesFM matches or exceeds trained models zero-shot especially in low-data regimes, and participant-level fine-tuning reduces per-feature RMSE by 16–60%. The study is the first to jointly evaluate modern deep learning, foundation models, and personalisation for this domain.
PatchTSMixer in HuggingFace
Hugging Face introduces PatchTSMixer, a lightweight MLP-Mixer-based model for multivariate time-series forecasting, now available in the Transformers library. The model is designed for efficient patch-based mixing of temporal and channel information. This integration expands Hugging Face's time-series modeling capabilities alongside the previously added PatchTST model.
Temporally Ordered Pre-training Improves LLM Factual Freshness (Kairos)
Researchers from Kyutai pre-train 6B-parameter models on temporally ordered Common Crawl snapshots and compare them against standard shuffled pre-training baselines. They introduce a benchmark of over 7,000 temporally grounded questions to evaluate whether models correctly associate facts with their corresponding time periods. Results show sequentially trained models match shuffled baselines on general language understanding while exhibiting more up-to-date and temporally precise factual knowledge. Code, checkpoints, and datasets are released under the Kairos project.
Distilling Tabular Foundation Models for Structured Health Data
This paper investigates knowledge distillation from tabular foundation models (TFMs) to lightweight student models for healthcare applications. The authors address context leakage in in-context TFMs via stratified out-of-fold teacher labeling, evaluating across 19 healthcare datasets, 6 TFM teachers, and 4 student families. Distilled students retain at least 90% of teacher AUC while running 26× faster on CPU, with preserved calibration and fairness properties. Multi-teacher ensembles do not consistently outperform the best single teacher.

